RADIESSE® (+) Plus


Manufacturer: Merz Pharma
Active Substance(s) : Calcium hydroxylapatite, lidocaine
Pack Size: 1-0.8ml or 1-1.5ml prefilled syringe
Accessories: Package insert

SKU: N/A Category:


What is Radiesse® (+) Plus with Lidocaine?

Radiesse (+) with Lidocaine is a transparent, sterile, injectable gel made of calcium hydroxylapatite particles and the anesthetic Lidocaine. Inject Radiesse (+) with Lidocaine into wrinkles to restore a smoother appearance to aging skin, into areas of facial fat loss to restore volume, or into hands to reduce the looks of visible veins and bones. Only authorized personnel in accordance with local regulations should administer Radiesse (+) with Lidocaine injections.

What does this product come with?

  • 1-0.8cc or 1-1.5cc prefilled syringe
  • Packaging insert
  • Traceability labels

What are the benefits of this product?

Radiesse (+) with Lidocaine offers longer lasting results when compared to hyaluronic acid fillers; results can last up to a year or more. This product is also particularly suited to correct more severe wrinkles and folds as it possesses better volumizing properties. Supplemented with lidocaine, treatment with this product can now be a more comfortable experience for your patients. 

How does this product work?

Radiesse (+) with Lidocaine contains particles of synthetic calcium hydroxylapatite (CaHA), which is commonly used in medicine and is a component of bone and teeth. When you inject the dermal filler gel, the particles add volume beneath the skin, supporting the skin and smoothing the appearance of wrinkles or folds. Although the CaHA gradually breaks down within the body, since it had acted as a scaffold for collagen to grow, it leaves behind these collagen fibers to maintain the volume. During the injection itself, the lidocaine in Radiesse (+) 1.5ml with Lidocaine acts as an anesthetic, numbing the injection area to reduce needle pain and discomfort that the patient might feel.

What are the ingredients?

Synthetic calcium hydroxylapatite suspended in a gel carrier with lidocaine.

Use Instructions

How to inject/administer this product

Only qualified medical professionals should inject this dermal filler. To use Radiesse (+) with Lidocaine, first disinfect the treatment area. Open the foil pouch containing the dermal filler syringe, remove the Luer syringe cap from the end of the syringe, then twist on a 27G needle onto the Luer lock fitting, ensuring it is tightened securely. Be sure to inject Radiesse (+) with Lidocaine into the deep dermis to avoid nodule formation and discoloration of the skin, and do not overcorrect. Insert the needle at a thirty degree angle in the wrinkle or fold, and slowly inject the gel while withdrawing the needle, leaving a line of dermal filler. Repeat, adding additional lines of dermal filler until you have the amount of augmentation you need. Gently massage or mold the implant to help contour the skin. Refer to your Radiesse (+) with Lidocaine leaflet for complete instructions.

When should I use this product?

Doctors, such as plastic surgeons and dermatologists, use Radiesse (+) with Lidocaine to reduce the appearance of facial folds and wrinkles. This dermal filler can act as an alternative to rhinoplasty or other plastic surgery as it corrects imperfections with a needle in an in-office procedure. Traditionally, doctors have used Radiesse (+) with Lidocaine to correct lipoatrophy, also known as facial fat loss, in HIV patients.

What areas can I treat with this product?

Radiesse is used in the treatment of facial wrinkling. This can include the nasolabial folds between the nose and the mouth; the radial lip lines above the upper lip; and marionette lines, or smile lines, at the corners of the mouth. Radiesse (+) with Lidocaine can also help add volume, such as restoring hollow cheeks caused by fat atrophy; filling acne scars and other depressions or blemishes; contouring the jawline; correcting indentations or unevenness on the nose or chin; and reducing the appearance of tendons and veins that become prominent as hands age.

How long do results last?

Radiesse (+) with Lidocaine usually lasts around 18 months or longer, so your patient should return about every 1 and a half to 2 years for another dermal filler treatment to maintain their results.

Frequently Asked Questions

Who is an ideal candidate for this product?

To be considered for a treatment with Radiesse, individuals should be above the age of 18 and have a healthy immune system. You should not treat patients with Radiesse (+) with Lidocaine who are allergic or hypersensitive to any of it ingredients, or who have a history of serious allergic reaction or anaphylaxis. Do not use Radiesse (+) with Lidocaine to treat pregnant or breastfeeding patients, or in children under 18 because researchers have not studied the safety of this filler in these groups.

Why should I purchase this product?

Radiesse offers an alternative to hyaluronic acid-based dermal fillers that may not be suitable for some patients. Radiesse has been shown to produce equivalent results with less volume, meaning that this product provides better value with each syringe.       

Are there any side effects?

Your patient could experience Radiesse (+) with Lidocaine side effects at the injection site such as pain, tenderness, swelling, discoloration, and itching, although these should usually resolve within about a week. Applying ice or a cool compress to the treatment area for the next 24 hours can help. If you incorrectly place the filler, your patient could have some lumpiness at the injection site. According to the manufacturer, there have not yet been reported cases of serious granulomatous reactions, with masses of immune cells accumulating at the site of inflammation. The injection could also cause an infection. These may not be all the potential Radiesse (+) with Lidocaine side effects.

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Additional information


1 pack of 0.8ml at $150, 5 packs of 0.8ml at $135/pack, 10 packs of 0.8ml at $120/pack, 20 packs of 0.8ml at $110/pack, 1 pack of 1.5ml at $200, 5 packs of 1.5ml at $185/pack, 10 packs of 1.5ml at $170/pack, 20 packs of 1.5ml at $160/pack